Description

2,3-Dihydro-1-Benzofuran-7-Carbonyl Chloride is a versatile and highly reactive organic intermediate, specifically an acid chloride derivative of the benzofuran scaffold. Its primary value lies in its role as a key building block for the synthesis of more complex molecules, enabling the rapid introduction of the 2,3-dihydrobenzofuran-7-carboxamide or ester moiety. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require a reliable, high-purity reagent for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the benzofuran core for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a coupling reagent or labeling agent for modifying proteins, peptides, and other biomolecules in research settings.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals for clients.

Basic Information

Product Name	2,3-Dihydro-1-Benzofuran-7-Carbonyl Chloride
CAS No.	123266-63-7
Molecular Formula	C9H7ClO2
Molecular Weight	182.60 g/mol
Synonyms	7-Carboxy-2,3-dihydrobenzofuran chloride; 2,3-Dihydrobenzofuran-7-carbonyl chloride; 2,3-Dihydro-7-benzofurancarbonyl chloride; 7-Chlorocarbonyl-2,3-dihydrobenzofuran; 2,3-Dihydro-1-benzofuran-7-carboxylic acid chloride; Dihydrobenzofuran-7-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1-Benzofuran-7-Carbonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) documenting purity, assay, and impurity profiles are available upon request to support your quality and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and separated from strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	95.0 - 102.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.