Description

2'-Deoxyisocytidine is a synthetic nucleoside analog, a key building block in nucleic acid chemistry and pharmaceutical research. Its primary value lies in its role as a modified cytidine derivative, enabling the study of DNA structure, function, and the development of novel therapeutic agents. This compound is essential for researchers and manufacturers in the fields of antiviral drug development, oligonucleotide synthesis, and biochemical research, where precise molecular tools are required.

Application

• Oligonucleotide Synthesis: A critical phosphoramidite monomer for the solid-phase synthesis of modified DNA and RNA strands for research and therapeutic applications.
• Antiviral Drug Development: Serves as a precursor or active pharmaceutical ingredient (API) intermediate in the synthesis of nucleoside analog antiviral agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate DNA replication, repair mechanisms, and polymerase activity.
• Proteomics & Genomics: Employed in the preparation of probes, primers, and other molecular tools for genetic analysis and diagnostic assay development.
• Pharmaceutical Intermediates: A high-purity building block for the cGMP-compliant synthesis of more complex active pharmaceutical ingredients (APIs).
• Academic Research: Fundamental compound for university and institutional labs studying nucleic acid chemistry, mutagenesis, and molecular biology.

Basic Information

Product Name	2'-Deoxyisocytidine
CAS No.	123075-23-0
Molecular Formula	C9H13N3O4
Molecular Weight	227.22 g/mol
Synonyms	2'-Deoxy-5-methylisocytidine; 1-(2-Deoxy-β-D-ribofuranosyl)-5-methyl-2-pyrimidinone; 5-Methyl-2'-deoxyisocytidine; Iso-dC; diC; 2'-Deoxy-5-methyl-iso-cytidine; 5-Methyldeoxyisocytidine; 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-methyl-2(1H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our 2'-Deoxyisocytidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to ensure compliance with your research or production requirements. Specifications can be tailored to meet specific project needs, including higher purity grades for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.