Description

Bicyclo[3.1.1]Heptane-1-Carbonyl Chloride (9Ci) is a highly reactive and versatile bicyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its unique strained bicyclic framework makes it an invaluable precursor for constructing complex molecular architectures with specific three-dimensional geometries. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly those requiring rigid, bicyclic scaffolds for target binding.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides where the bicyclo[3.1.1]heptane core imparts stability and bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique thermal and mechanical properties.
• Ligand and Catalyst Development: Employed to create sophisticated chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to tag or modify biomolecules for studying biological pathways and protein function.
• Flavor and Fragrance Chemistry: Acts as a precursor for synthesizing complex terpenoid-like aroma compounds.

Basic Information

Product Name	Bicyclo[3.1.1]Heptane-1-Carbonyl Chloride (9Ci)
CAS No.	123033-33-0
Molecular Formula	C8H11ClO
Molecular Weight	158.62 g/mol
Synonyms	1-Bicyclo[3.1.1]heptanecarbonyl chloride; Norbornane-1-carbonyl chloride (ambiguous, but related); Bicyclo[3.1.1]heptane-1-carboxylic acid chloride; 1-Carboxybicyclo[3.1.1]heptane chloride; 1-Chlorocarbonylbicyclo[3.1.1]heptane; (1R,5S)-Bicyclo[3.1.1]heptane-1-carbonyl chloride (for specific enantiomer); Bicyclo[3.1.1]heptan-1-ylcarbonyl chloride
EINECS	Contact for details

Quality Control

Our Bicyclo[3.1.1]Heptane-1-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and process chemistry. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Typical 97-99%)
Water Content (KF)	≤ 0.5%
Acid Value	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.