Description

Phoslactomycin A is a potent and structurally unique natural product belonging to the phosphopolyketide class of antibiotics. This compound matters for its significant biological activity, primarily functioning as a selective inhibitor of eukaryotic protein phosphatases, which makes it a valuable tool in biochemical and pharmacological research. It is needed by researchers in pharmaceutical development, biotechnology, and academic institutions focused on signal transduction pathways, cancer research, and the discovery of novel therapeutic agents.

Application

• Biochemical Research: Used as a selective and potent inhibitor of protein phosphatase 2A (PP2A) and other serine/threonine phosphatases in cell signaling studies.
• Anticancer Agent Discovery: Investigated for its antiproliferative and apoptosis-inducing effects against various cancer cell lines, serving as a lead compound for novel oncology therapeutics.
• Antifungal Research: Studied for its activity against fungal pathogens, contributing to the development of new antifungal agents.
• Mechanistic Studies: Employed as a molecular probe to elucidate the role of specific phosphatases in cellular processes like cell cycle regulation and metabolism.
• Pharmaceutical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in drug discovery pipelines.

Basic Information

Product Name	Phoslactomycin A
CAS No.	122856-25-1
Molecular Formula	C₂₄H₃₉NO₈P
Molecular Weight	500.54 g/mol
Synonyms	Phoslactomycin A; FR-901448; L-688,768; Phosphazomycin A; (2E,4E,6E,8E)-9-[(2R,3S,4S,5S,6R)-4,5-Dihydroxy-6-methyl-3-(phosphonooxy)oxan-2-yl]-3-[(2S,3S)-3-hydroxy-2-methylpentylidene]-1-(2-methyl-1-oxopropyl)-4,8-dimethylnona-2,4,6,8-tetraenamide
EINECS	Contact for details

Quality Control

Our Phoslactomycin A is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-free environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider storage under an inert atmosphere. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.