Description

2-Phenylpyrimidine-5-Carbonyl Chloride 97% is a high-purity, reactive organic intermediate belonging to the pyrimidine class of heterocyclic compounds. This compound is a critical building block in advanced organic synthesis, valued for its ability to introduce the 2-phenylpyrimidine-5-carbonyl moiety into target molecules. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting kinases and other enzymes.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed to create novel pyrimidine-based ligands for metal catalysis and coordination chemistry.
• Chemical Biology Probes: Useful for synthesizing molecular probes and labeled compounds for biochemical and diagnostic research.

Basic Information

Product Name	2-Phenylpyrimidine-5-Carbonyl Chloride 97%
CAS No.	122774-00-9
Molecular Formula	C11H7ClN2O
Molecular Weight	218.64 g/mol
Synonyms	5-(Chlorocarbonyl)-2-phenylpyrimidine; 2-Phenylpyrimidine-5-carboxylic acid chloride; 2-Phenyl-5-pyrimidinecarbonyl chloride; 5-Carboxy-2-phenylpyrimidine chloride; Pyrimidine-5-carbonyl chloride, 2-phenyl-; (2-Phenylpyrimidin-5-yl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Phenylpyrimidine-5-Carbonyl Chloride 97% is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the specified 97% minimum purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.