Description

(3A,4B,5B,7A,12A)-3,4,7,12-Tetrahydroxy-Cholan-24-Oic Acid is a high-purity, multi-hydroxylated bile acid derivative with significant value as a key pharmaceutical intermediate and research chemical. Its specific stereochemistry and functional groups make it a critical building block for the synthesis of advanced therapeutic agents and biochemical probes. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors developing novel treatments and diagnostic tools.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel therapeutic bile acid analogs and steroid-based drugs.
• Biochemical Research: Used as a standard or reagent in metabolic pathway studies, enzyme inhibition assays, and receptor binding research.
• Reference Standard: Employed in analytical laboratories for method development, validation, and quality control testing of related compounds.
• Fine Chemical Synthesis: Acts as a chiral starting material or advanced intermediate for the production of complex, high-value specialty chemicals.
• Metabolite Studies: Utilized in research investigating bile acid metabolism, liver function, and related disorders.

Basic Information

Product Name	(3A,4B,5B,7A,12A)-3,4,7,12-Tetrahydroxy-Cholan-24-Oic Acid
CAS No.	122742-19-2
Molecular Formula	C₂₄H₄₀O₆
Molecular Weight	424.57 g/mol
Synonyms	3α,4β,5β,7α,12α-Pentahydroxycholan-24-oic Acid; 3α,4β,5β,7α,12α-Pentahydroxy-5β-cholan-24-oic Acid; 5β-Cholan-24-oic acid-3α,4β,5β,7α,12α-pentol; Tetrahydroxycholanic Acid (isomer specific); 3,4,7,12-Tetrahydroxycholanic Acid; Bile Acid Derivative; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our (3A,4B,5B,7A,12A)-3,4,7,12-Tetrahydroxy-Cholan-24-Oic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting standards for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.