Description

N6-Benzoyl-3'-Fluoro-2',3'-Dideoxyadenosine is a chemically modified nucleoside analog, specifically designed as a key synthetic intermediate. This compound is of significant value in pharmaceutical research and development, particularly for the synthesis of novel antiviral and anticancer agents. It is primarily needed by research institutions, pharmaceutical companies, and CROs (Contract Research Organizations) engaged in nucleoside chemistry and the development of therapeutic nucleotides.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of modified nucleoside-based prodrugs and active pharmaceutical ingredients (APIs).
• Antiviral Research: Used in the development of nucleotide analogs targeting viral polymerases, with potential applications against HIV, HBV, and HCV.
• Oncology Research: Serves as a precursor for investigational antimetabolite drugs designed to inhibit cancer cell proliferation.
• Biochemical Tool: Employed in enzymatic studies to investigate substrate specificity and inhibition mechanisms of nucleoside/nucleotide-processing enzymes.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies to optimize the potency and selectivity of nucleoside therapeutics.
• Labeled Compound Synthesis: A potential starting material for the preparation of isotopically labeled (e.g., 13C, 15N, 3H) nucleosides for metabolic tracing and pharmacokinetic studies.

Basic Information

Product Name	N6-Benzoyl-3'-Fluoro-2',3'-Dideoxyadenosine
CAS No.	122712-71-4
Molecular Formula	C17H16FN5O3
Molecular Weight	357.34 g/mol
Synonyms	3'-Fluoro-2',3'-dideoxy-N6-benzoyladenosine; 9-[(2R,5S)-5-Fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl]-N-benzyl-9H-purin-6-amine; 2',3'-Dideoxy-3'-fluoroadenosine N6-benzoyl derivative; Bz-3'-F-ddA; N6-Benzoyl-3'-fluoro-ddA; 3'-F-ddA(Bz); Adenosine, 2',3'-dideoxy-3'-fluoro-, 6-(benzoyl)-
EINECS	Contact for details

Quality Control

Our N6-Benzoyl-3'-Fluoro-2',3'-Dideoxyadenosine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.