Description

3'-Deoxy-3'-Fluoro-2-Chloroadenosine is a chemically modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical building block and intermediate for synthesizing novel antiviral and anticancer agents. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in drug discovery programs targeting viral infections and oncology.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel nucleoside-based antiviral and anticancer prodrugs.
• Antiviral Research: Investigated for its potential activity against a range of DNA and RNA viruses due to its modified sugar moiety.
• Oncology Research: Used in the development of chemotherapeutic agents that target cellular DNA/RNA synthesis and repair mechanisms.
• Biochemical Tool: Employed in enzymatic studies to understand substrate specificity and inhibition of nucleoside/nucleotide-processing enzymes.
• Medicinal Chemistry: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize pharmacokinetic properties.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	3'-Deoxy-3'-Fluoro-2-Chloroadenosine
CAS No.	122654-30-2
Molecular Formula	C10H11ClFN5O3
Molecular Weight	303.68 g/mol
Synonyms	2-Chloro-3'-deoxy-3'-fluoroadenosine; 2-Chloro-3'-fluoro-3'-deoxyadenosine; 9-[(2R,3R,4S,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-chloro-9H-purin-6-amine; 3'-Fluoro-2-chloroadenosine; 2-Chloro-3'-fluoroadenosine; 3'-F-2-Cl-Ado; Contact for additional names.
EINECS	Contact for details

Quality Control

Our 3'-Deoxy-3'-Fluoro-2-Chloroadenosine is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.