Description

3'-Deoxy-3'-Fluoro-N6-Methyladenosine is a chemically modified nucleoside analog of significant interest in pharmaceutical research and development. This compound matters as a key synthetic intermediate and building block for the creation of novel antiviral and anticancer therapeutics. It is primarily needed by research institutions, pharmaceutical companies, and biotechnology firms engaged in the synthesis of modified RNA molecules, prodrug development, and targeted metabolic studies. The precise structural modifications offer unique properties for probing biological mechanisms and developing advanced drug candidates.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving adenosine deaminase or kinase pathways.
• Prodrug Development: Serves as a precursor molecule in the design of targeted prodrugs for improved therapeutic efficacy and reduced side effects.
• Antiviral Agent Synthesis: A key intermediate for developing compounds active against RNA viruses, leveraging its modified sugar moiety.
• Molecular Probe: Utilized in metabolic labeling and tracing studies within cellular systems due to its fluorinated and methylated structure.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the pharmacokinetic and pharmacodynamic profiles of nucleoside analogs.

Basic Information

Product Name	3'-Deoxy-3'-Fluoro-N6-Methyladenosine
CAS No.	122654-27-7
Molecular Formula	C11H14FN5O3
Molecular Weight	283.26 g/mol
Synonyms	3'-Deoxy-3'-fluoroadenosine, N6-methyl derivative; 3'-Fluoro-3'-deoxy-N6-methyladenosine; 9-[(3-Deoxy-3-fluoro-β-D-ribofuranosyl)]-N6-methyladenine; 3'-F-3'-dA(N6-Me); N6-Methyl-3'-deoxy-3'-fluoroadenosine; 3'-Fluoro-N6-methyl-3'-deoxyadenosine; 1-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-N6-methyladenine
EINECS	Contact for details

Quality Control

Our 3'-Deoxy-3'-Fluoro-N6-Methyladenosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.