Description

2',3'-Dideoxyribosylinosine 5'-Triphosphate is a modified nucleoside triphosphate analog, a critical building block for nucleic acid research and development. This compound is essential for studying viral replication mechanisms, particularly for reverse transcriptase enzymes, and serves as a key intermediate in the synthesis of nucleotide-based therapeutics. It is primarily utilized by research institutions, diagnostic developers, and pharmaceutical companies engaged in antiviral drug discovery, molecular biology, and biochemical assay development.

Application

• Antiviral Research: Used as a substrate or inhibitor in studies of HIV and other retroviral reverse transcriptase activity.
• Molecular Biology: Acts as a specialized nucleotide for in vitro transcription, PCR, and sequencing applications investigating chain termination.
• Biochemical Assay Development: Employed in enzymatic assays to probe the kinetics and specificity of DNA polymerases.
• Nucleotide Analog Synthesis: Serves as a crucial precursor in the chemical and enzymatic synthesis of novel dideoxynucleotide analogs for therapeutic exploration.
• Diagnostic Reagents: Incorporated into diagnostic kits for the detection and quantification of specific viral loads.

Basic Information

Product Name	2',3'-Dideoxyribosylinosine 5'-Triphosphate
CAS No.	122406-02-4
Molecular Formula	C15H22N5O13P3
Molecular Weight	589.28 g/mol
Synonyms	ddITP; 2',3'-Dideoxyinosine 5'-triphosphate; 2',3'-Dideoxyinosine triphosphate; Dideoxyinosine triphosphate; 9-[(2,3-Dideoxy-β-D-erythro-pentofuranosyl)hypoxanthine] 5'-triphosphate; Inosine 2',3'-dideoxy-5'-triphosphate
EINECS	Contact for details

Quality Control

Our 2',3'-Dideoxyribosylinosine 5'-Triphosphate is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency for research applications. Each lot is characterized by HPLC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 90% (by UV spectrophotometry)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, TE buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.