Description

5-Azido-5-Deoxy-2,3-o-Isopropylidene-D-Lyxono-1,4-Lactone is a specialized, high-value chiral building block and synthetic intermediate. This compound matters for its role in the synthesis of complex nucleoside analogs and other biologically active molecules, offering a unique azido functional handle for further chemical transformations. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of antiviral agents, modified oligonucleotides, and carbohydrate-based therapeutics.

Application

• Nucleoside Analog Synthesis: A key chiral precursor for the development of novel antiviral and anticancer nucleoside drugs.
• Carbohydrate Chemistry: Used in the synthesis of modified sugars and complex oligosaccharides for biochemical research.
• Click Chemistry Substrate: The azido group enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and material science applications.
• Pharmaceutical Intermediates: Serves as a critical building block in multi-step synthetic routes for active pharmaceutical ingredients (APIs).
• Glycobiology Research: Employed in studies exploring glycosylation processes and carbohydrate-protein interactions.
• Probe and Diagnostic Agent Development: Utilized to create labeled compounds for imaging and diagnostic assays.

Basic Information

Product Name	5-Azido-5-Deoxy-2,3-o-Isopropylidene-D-Lyxono-1,4-Lactone
CAS No.	122194-04-1
Molecular Formula	C8H11N3O4
Molecular Weight	213.19 g/mol
Synonyms	5-Azido-5-deoxy-2,3-O-isopropylidene-D-lyxono-1,4-lactone; 5-Azido-5-deoxy-1,2-O-isopropylidene-α-D-lyxofuranurono-6,3-lactone; D-Lyxono-1,4-lactone, 5-azido-5-deoxy-2,3-O-(1-methylethylidene)-; 2,3-O-Isopropylidene-5-azido-5-deoxy-D-lyxono-1,4-lactone; 5-Azido-5-deoxy-2,3-O-isopropylidene-D-lyxono-γ-lactone
EINECS	Contact for details

Quality Control

Our 5-Azido-5-Deoxy-2,3-o-Isopropylidene-D-Lyxono-1,4-Lactone is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.