Description

3,N(4)-Propanodeoxycytidine 5'-Monophosphate is a chemically modified nucleoside monophosphate analog, a key building block in advanced oligonucleotide synthesis and medicinal chemistry research. This compound is valued for its role in creating modified nucleic acid sequences with enhanced stability and specific biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antisense oligonucleotides, siRNA, and other therapeutic nucleic acid platforms.

Application

• Oligonucleotide Synthesis: A critical phosphoramidite precursor for the solid-phase synthesis of modified DNA and RNA strands.
• Antisense Therapy Development: Used in research to create oligonucleotides that target and modulate specific gene expression.
• siRNA and miRNA Research: Incorporated into small interfering RNA (siRNA) or microRNA (miRNA) to improve nuclease resistance and pharmacokinetic properties.
• Medicinal Chemistry & Drug Discovery: Serves as a scaffold for developing novel nucleoside-based antiviral or anticancer agents.
• Diagnostic Probe Development: Used in the design of labeled probes for genetic testing and molecular diagnostics.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate nucleic acid metabolism and repair pathways.

Basic Information

Product Name	3,N(4)-Propanodeoxycytidine 5'-Monophosphate
CAS No.	121730-59-4
Molecular Formula	C12H18N3O7P
Molecular Weight	347.26 g/mol
Synonyms	3,N4-Propanodeoxycytidine 5'-Monophosphate; 3,N(4)-PropanodCMP; 5'-dCMP Propano Adduct; 3,N4-Propano-2'-deoxycytidine 5'-monophosphate; 1-(2-Deoxy-5-O-phosphono-β-D-erythro-pentofuranosyl)-4-(2-hydroxyethyl)-2(1H)-pyrimidinone; Modified Deoxycytidine Monophosphate; Propanodeoxycytidine Monophosphate
EINECS	Contact for details

Quality Control

Our 3,N(4)-Propanodeoxycytidine 5'-Monophosphate is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality guidelines suitable for research-grade biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccant and under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.