Description

Benzoyl Fluoride, 3,4,5-Trifluoro- (9Ci) CAS NO 121579-84-8 is a high-purity fluorinated aromatic building block, a key intermediate in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the benzoyl fluoride core, enabling precise modification of molecular properties for performance-driven applications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing next-generation active ingredients, as well as in materials science for creating specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl and fluoride groups enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a key precursor for fluorinated liquid crystal compounds used in high-performance displays (LCDs) due to its ability to modify dielectric anisotropy and viscosity.
• Polymer & Material Science: Employed in the synthesis of specialty polymers, including polyarylates and polyimides, to impart improved thermal stability, chemical resistance, and optical properties.
• Organic Electronics: Acts as a building block for electron-transport materials and semiconductors in OLEDs and organic photovoltaics.
• Chemical Research & Development: A versatile reagent for introducing the 3,4,5-trifluorobenzoyl moiety in medicinal chemistry and material science R&D programs.

Basic Information

Product Name	Benzoyl Fluoride, 3,4,5-Trifluoro- (9Ci)
CAS No.	121579-84-8
Molecular Formula	C7H2F4O
Molecular Weight	178.09 g/mol
Synonyms	3,4,5-Trifluorobenzoyl Fluoride; 3,4,5-Trifluorobenzoic Acid Fluoride; Benzoyl Fluoride, 3,4,5-Trifluoro-; 3,4,5-Trifluorobenzoyl Fluoride (9CI); 3,4,5-Trifluorobenzoic Fluoride; α,3,4,5-Tetrafluorotoluene; Perfluorotoluene (incorrect but common alias); 3,4,5-Trifluorobenzenecarbonyl Fluoride
EINECS	Contact for details

Quality Control

Every batch of 3,4,5-Trifluorobenzoyl Fluoride is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from GC, HPLC, NMR, and FTIR analyses to verify identity, purity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for advanced synthetic applications, supporting your R&D and production with reliable and consistent performance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.