Description

5-(2-Iodovinyl)-1-(2'-Fluoro-2'-Deoxyuridine) is a sophisticated nucleoside analog building block designed for advanced pharmaceutical research and development. This compound is critical for the synthesis of novel antiviral and anticancer agents, offering researchers a versatile scaffold for probing biological mechanisms and developing targeted therapies. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Medicinal Chemistry Research: Used as a building block for structure-activity relationship (SAR) studies to optimize drug efficacy and selectivity.
• Biochemical Probe Development: Employed in the creation of molecular probes to study enzyme mechanisms, particularly those involving thymidylate synthase and viral polymerases.
• Antiviral Agent Synthesis: Integral to the development of potential treatments for viral infections, leveraging the modified nucleoside structure.
• Radiopharmaceutical Precursor: The iodine moiety provides a potential handle for radiolabeling (e.g., with I-125 or I-131) for diagnostic imaging or targeted radiotherapy research.
• Academic & Institutional Research: Serves as a high-value reference standard and synthetic target in graduate-level and post-doctoral research programs.

Basic Information

Product Name	5-(2-Iodovinyl)-1-(2'-Fluoro-2'-Deoxyuridine)
CAS No.	121563-65-3
Molecular Formula	C11H11FIN2O5
Molecular Weight	397.12 g/mol
Synonyms	5-(2-Iodovinyl)-2'-Fluoro-2'-deoxyuridine; 5-(2-Iodovinyl)-1-((2R,4S,5R)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 2'-Fluoro-5-(2-iodovinyl)-2'-deoxyuridine; IVFRU; FIVdU; 5-(2-Iodovinyl)-1-(2-deoxy-2-fluoro-β-D-ribofuranosyl)uracil
EINECS	Contact for details

Quality Control

Our 5-(2-Iodovinyl)-1-(2'-Fluoro-2'-Deoxyuridine) is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.