Description

3,7,12,23-Tetrahydroxycholestanoic Acid is a hydroxylated bile acid derivative, a key intermediate in the study of cholesterol metabolism and bile acid biosynthesis. This compound is of significant value for research and development in metabolic pathways and as a potential precursor for specialized biochemicals. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on developing diagnostic tools or therapeutic agents for liver and metabolic disorders.

Application

• Biochemical Research: Critical intermediate for studying bile acid synthesis, cholesterol catabolism, and related metabolic disorders.
• Pharmaceutical Development: Serves as a reference standard and a potential synthetic precursor for novel therapeutic agents targeting liver function.
• Diagnostic Reagent Manufacturing: Used in the production of calibrators and controls for clinical assays measuring bile acid profiles.
• Metabolic Pathway Analysis: A tool for in vitro and in vivo studies to elucidate the role of specific hydroxylation patterns in bile acid physiology.
• Fine Chemical Synthesis: Building block for the synthesis of more complex, structurally modified bile acid analogs for specialized applications.

Basic Information

Product Name	3,7,12,23-Tetrahydroxycholestanoic Acid
CAS No.	121500-92-3
Molecular Formula	C27H46O6
Molecular Weight	466.66 g/mol
Synonyms	3α,7α,12α,23-Tetrahydroxy-5β-cholestan-26-oic Acid; 23-Tetrahydroxycoprostanic Acid; 3,7,12,23-Tetrahydroxycoprostanic Acid; (23R)-3α,7α,12α,23-Tetrahydroxy-5β-cholestan-26-oic Acid; Tetrahydroxycholestanoic Acid
EINECS	Contact for details

Quality Control

Our 3,7,12,23-Tetrahydroxycholestanoic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.