Description

Morpholine, 4-(Chlorodifluoroacetyl)- (9Ci) is a specialized organofluorine building block derived from morpholine, featuring a reactive chlorodifluoroacetyl moiety. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors where the introduction of fluorine atoms is crucial for modulating biological activity and stability. It serves the needs of research chemists and process development scientists engaged in creating novel active ingredients, advanced materials, and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of fluorinated drug candidates, including potential protease inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoroacetate group can enhance metabolic stability and efficacy.
• Material Science Research: Employed in the synthesis of specialty polymers and functional materials that require fluorinated morpholine derivatives.
• Organic Synthesis Building Block: Serves as a versatile reagent for introducing the N-(chlorodifluoroacetyl)morpholine group into more complex molecular architectures.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel fluorinated compounds.

Basic Information

Product Name	Morpholine, 4-(Chlorodifluoroacetyl)- (9Ci)
CAS No.	121412-23-5
Molecular Formula	C6H8ClF2NO2
Molecular Weight	199.58 g/mol
Synonyms	4-(Chlorodifluoroacetyl)morpholine; N-(Chlorodifluoroacetyl)morpholine; Morpholine, 4-(chlorodifluoroacetyl)-; Chlorodifluoroacetic acid morpholide; 2-Chloro-2,2-difluoro-N-morpholinoacetamide
EINECS	Contact for details

Quality Control

Our Morpholine, 4-(Chlorodifluoroacetyl)- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing specific results for purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.