Description

Pacidamycin 2 is a specialized antibiotic compound belonging to the uridyl peptide class, known for its unique mechanism of action targeting bacterial cell wall synthesis. This makes it a valuable tool for advanced research into novel antibacterial pathways and resistance mechanisms. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies engaged in the discovery and development of next-generation antimicrobial agents. The compound is supplied under stringent quality controls to ensure reliability for critical scientific applications.

Application

• Antibacterial Research & Development: A key reference standard and active compound for studying novel modes of action against multidrug-resistant bacteria.
• Mechanism of Action Studies: Used to investigate the inhibition of the bacterial translocase MraY, a validated target for antibiotic discovery.
• Biochemical Assay Development: Serves as a critical component in high-throughput screening assays to identify new antibacterial leads or potentiators.
• Microbiology Research: Employed in academic and industrial labs to explore bacterial physiology and the genetics of cell wall biosynthesis.
• Structure-Activity Relationship (SAR) Analysis: Provides a core scaffold for medicinal chemistry programs aimed at optimizing antibiotic potency and pharmacokinetics.
• Quality Control & Reference Standard: Used as an analytical standard in HPLC or LC-MS methods for quality assurance of related compounds or fermentation products.

Basic Information

Product Name	Pacidamycin 2
CAS No.	121264-06-0
Molecular Formula	C₄₀H₅₀N₁₀O₁₅
Molecular Weight	906.89 g/mol
Synonyms	Pacidamycin A; Antibiotic MJ 347-81F4; Uridyl peptide antibiotic Pacidamycin 2; 5'-O-[(4R,5R)-4,5-Dihydroxy-2-cyclohexen-1-ylcarbonyl]adenosyl-uridyl-alanyl-tryptophyl-glycyl-m-tyrosyl-dehydrobutyrine; MJ 347-81F4
EINECS	Contact for details

Quality Control

Every batch of Pacidamycin 2 is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency for research use. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific results for purity, identity, and impurities are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to reach room temperature before opening to prevent condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.