Description

Pacidamycin 1 is a specialized natural product antibiotic belonging to the uridyl peptide class. Its primary value lies in its potent and selective antibacterial activity, particularly against Pseudomonas aeruginosa, a significant pathogen in clinical and research settings. This compound is of high interest to researchers in pharmaceutical development, microbiology, and biochemistry for studying novel antibiotic mechanisms and resistance pathways. Pacidamycin 1 CAS NO 121264-05-9 serves as a critical reference standard and a lead compound in the discovery of new anti-infective agents.

Application

• Pharmaceutical Research & Development: As a lead compound for developing new antibiotics targeting multidrug-resistant Gram-negative bacteria.
• Microbiological Studies: Used in research to investigate bacterial cell wall biosynthesis inhibition and mechanisms of action against Pseudomonas aeruginosa.
• Biochemical Research: Serves as a tool compound for studying the MraY translocase enzyme, a key target in bacterial peptidoglycan synthesis.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and antibiotic discovery.

Basic Information

Product Name	Pacidamycin 1
CAS No.	121264-05-9
Molecular Formula	C₄₀H₅₄N₁₀O₁₇
Molecular Weight	946.92 g/mol
Synonyms	Pacidamycin; Antibiotic MJ 347-81F4; MJ 347-81F4; Pacidamycin 1; Uridyl peptide antibiotic; 5'-O-[N-[3-[[(2S,3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]uridine
EINECS	Contact for details

Quality Control

Our Pacidamycin 1 is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS). A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Solubility	Soluble in DMSO, Methanol; Slightly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.