Description

2'-Valeryl-6-Methoxypurine Arabinoside is a chemically modified nucleoside analog, a key building block in advanced pharmaceutical research and development. This compound is valued for its role as a versatile synthetic intermediate, enabling the creation of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral and anticancer drugs, as well as in biochemical studies exploring nucleoside metabolism and function.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleoside kinases and other metabolic pathways.
• Antiviral Agent Development: Serves as a structural scaffold for modifying activity and selectivity against specific viral targets.
• Anticancer Research: Investigated for its potential to be incorporated into DNA/RNA, disrupting replication in rapidly dividing cancer cells.
• Prodrug Synthesis: The valeryl moiety can be utilized in prodrug strategies to enhance bioavailability and targeted delivery.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2'-Valeryl-6-Methoxypurine Arabinoside
CAS No.	121032-22-2
Molecular Formula	C₁₇H₂₂N₄O₆
Molecular Weight	378.38 g/mol
Synonyms	6-Methoxy-9-(5-O-valeryl-β-D-arabinofuranosyl)purine; 2'-O-Valeryl-6-methoxypurine arabinoside; 6-Methoxypurine Arabinoside 2'-Valerate; 9-[(2R,3S,4R,5R)-5-[(2S)-2-Methylbutanoyloxymethyl]-3,4-dihydroxyoxolan-2-yl]-6-methoxypurine; Valeryl-6-MP-Ara; 6-Methoxy-9-β-D-arabinofuranosylpurine 2'-valerate
EINECS	Contact for details

Quality Control

Our 2'-Valeryl-6-Methoxypurine Arabinoside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.