Description

α-D-Galactopyranosylphenyl Isothiocyanate is a specialized glycosyl isothiocyanate derivative used as a critical biochemical reagent. This compound is valued for its role as a derivatization agent and a key intermediate in the synthesis of glycoconjugates and affinity ligands. It is primarily required by researchers and manufacturers in the fields of glycobiology, analytical chemistry, and pharmaceutical development for labeling and structural analysis.

Application

• Glycoprotein and Oligosaccharide Labeling: Acts as a derivatization reagent for the fluorescent or chromogenic tagging of reducing sugars for HPLC or MS analysis.
• Affinity Chromatography Ligand Synthesis: Serves as a key intermediate for coupling carbohydrate moieties to solid supports like agarose beads for lectin or antibody purification.
• Chemical Biology Probes: Used in the development of activity-based probes to study glycosidase enzymes or carbohydrate-binding proteins.
• Neoglycoconjugate Preparation: Facilitates the chemical synthesis of neoglycoproteins or glycolipids for immunological and vaccine research.
• Pharmaceutical Intermediate: Employed in the research and development of glycosidase inhibitors or other carbohydrate-based therapeutics.
• Diagnostic Reagent Manufacturing: Utilized in the production of components for diagnostic kits targeting specific carbohydrate antigens.

Basic Information

Product Name	α-D-Galactopyranosylphenyl Isothiocyanate
CAS No.	120967-92-2
Molecular Formula	C₁₃H₁₅NO₆S
Molecular Weight	313.33 g/mol
Synonyms	Phenyl 1-Thio-α-D-galactopyranoside Isothiocyanate; 1-Isothiocyanato-1-deoxy-α-D-galactopyranosylbenzene; α-D-Galactopyranosyl phenyl isothiocyanate; Phenyl α-D-galactopyranosyl isothiocyanate; Galactosylphenylisothiocyanate; α-Gal-PITC
EINECS	Contact for details

Quality Control

Our α-D-Galactopyranosylphenyl Isothiocyanate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and optical rotation measurement, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This material is moisture-sensitive and should be handled under dry conditions. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.