Description

Cytosine, 5-(Aminomethyl)- (6Ci) is a modified nucleobase derivative of cytosine, featuring an additional aminomethyl group at the 5-position. This structural modification makes it a valuable key synthetic intermediate and building block in advanced organic and medicinal chemistry. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and biotechnology sectors for the development of novel compounds, including nucleoside analogs and potential active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel nucleoside analogs and antiviral/anticancer drug candidates.
• Biochemical Research: Used in the study of nucleic acid chemistry, enzyme-substrate interactions, and the development of modified oligonucleotides.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new pesticides or plant growth regulators with specific biological activity.
• Diagnostic Reagent Synthesis: Employed in the creation of specialized probes, markers, or labeled compounds for diagnostic assays.
• Material Science: Potential use as a monomer or functional component in the development of specialty polymers and advanced materials.

Basic Information

Product Name	Cytosine, 5-(Aminomethyl)- (6Ci)
CAS No.	120908-32-9
Molecular Formula	C5H8N4O
Molecular Weight	140.14 g/mol
Synonyms	5-(Aminomethyl)cytosine; 5-(Aminomethyl)-2-hydroxy-4-aminopyrimidine; 4-Amino-5-(aminomethyl)-2(1H)-pyrimidinone; 2(1H)-Pyrimidinone, 4-amino-5-(aminomethyl)-; 5-(Aminomethyl)isocytosine; 5-Cytosinemethylamine
EINECS	Contact for details

Quality Control

Our Cytosine, 5-(Aminomethyl)- (6Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed specifications, including assay (HPLC), impurity profiles, and physical characterization. Our quality commitment supports applications in GMP-oriented synthesis and high-precision research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.