Description

4-Deacetyl-4-o-Isobutyrylkinamycin C is a structurally defined derivative of the kinamycin class of antibiotics, known for its unique anthraquinone-fused diazofluorene core. This compound is of significant interest in advanced pharmaceutical research and development due to its potent biological activity profile. It serves as a critical intermediate and reference standard for researchers in the fields of oncology, microbiology, and synthetic chemistry, enabling the study of novel mechanisms of action and the development of new therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of novel antibiotic and anticancer agents targeting DNA and topoisomerases.
• Biochemical Tool Compound: Used in microbiological and cellular assays to study bacterial resistance mechanisms and apoptotic pathways.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and compound identification via HPLC, LC-MS, or NMR.
• Academic & Institutional Research: Facilitates structure-activity relationship (SAR) studies to explore the pharmacophore of kinamycin derivatives.
• Preclinical Studies: Utilized in in vitro and in vivo models to evaluate efficacy, pharmacokinetics, and toxicity profiles of new drug candidates.

Basic Information

Product Name	4-Deacetyl-4-o-Isobutyrylkinamycin C
CAS No.	120901-49-7
Molecular Formula	C30H24N2O9
Molecular Weight	556.52 g/mol
Synonyms	4-Deacetyl-4-O-isobutyrylkinamycin C; Kinamycin C Derivative; 4-O-Isobutyryl-4-deacetylkinamycin C; Antibiotic Kinamycin Derivative; 3,6-Dideoxy-3-(2,6-dideoxy-4-O-[(2S)-2-methylbutanoyl]-β-D-ribo-hexopyranosyl)-4,8-dihydroxy-1-methyl-9,10-dioxo-9,10-dihydroanthracen-2-yl diazene; 1,4,5,8-Tetrahydroxy-2-[(1E)-2-(4-hydroxy-3,5-dimethoxyphenyl)ethenyl]-9,10-anthracenedione Derivative
EINECS	Contact for details

Quality Control

Our 4-Deacetyl-4-o-Isobutyrylkinamycin C is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.