Description

Withangulatin A is a naturally occurring withanolide, a class of bioactive steroidal lactones. This high-purity reference standard is critical for pharmaceutical research and analytical method development. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and natural product sectors for its role in studying biological pathways and ensuring product consistency.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and purity testing of drug substances and herbal extracts in compliance with pharmacopeial methods (e.g., USP, EP).
• Bioactivity Research: Serves as a key investigational compound in preclinical studies targeting inflammation, cancer, and neurological disorders.
• Analytical Method Development: Essential for developing and validating precise HPLC, LC-MS, and TLC methods for withanolide quantification.
• Natural Product Isolation & Characterization: Acts as a benchmark for the isolation and structural elucidation of withanolides from plant sources like Withania somnifera (Ashwagandha).
• Quality Control in Nutraceuticals: Employed to standardize and authenticate Ashwagandha-based dietary supplements, ensuring label claim accuracy and potency.

Basic Information

Product Name	Withangulatin A
CAS No.	120824-03-5
Molecular Formula	C28H38O7
Molecular Weight	486.60 g/mol
Synonyms	(20S,22R)-5α,6α-Epoxy-4β,17α,27-trihydroxy-1-oxowitha-2,24-dienolide; Withangulatin A; Withanolide A 4β,17α,27-trihydroxy-5α,6α-epoxy-1-oxo-; 5α,6α-Epoxy-4β,17α,27-trihydroxy-1-oxowitha-2,24-dienolide
EINECS	Contact for details

Quality Control

Our Withangulatin A is produced under strict quality management protocols. Each batch is characterized and tested to ensure high purity and consistency, suitable for use as a reference material. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.