Description

3-Pyridinecarbonylchloride,6-Amino-5-Chloro-(9Ci) is a high-purity, multifunctional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its reactive acid chloride and substituted pyridine structure, enabling the efficient construction of complex molecules for research and development. This compound is primarily needed by pharmaceutical, agrochemical, and specialty chemical manufacturers for the synthesis of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, receptor antagonists, and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators, leveraging its halogenated pyridine core.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of functional polymers, organic semiconductors, and metal-organic frameworks (MOFs) due to its bifunctional reactivity.
• Custom Synthesis and Contract Manufacturing: An essential reagent for fine chemical companies offering bespoke synthesis services for clients in life sciences.
• Academic and R&D Laboratories: Used in medicinal chemistry and synthetic methodology research to explore new chemical spaces and reaction pathways.

Basic Information

Product Name	3-Pyridinecarbonylchloride,6-Amino-5-Chloro-(9Ci)
CAS No.	120763-60-2
Molecular Formula	C7H4Cl2N2O
Molecular Weight	191.02 g/mol
Synonyms	5-Chloro-6-aminonicotinoyl chloride; 6-Amino-5-chloropyridine-3-carbonyl chloride; 2-Chloro-5-(chlorocarbonyl)pyridin-3-amine; 3-Amino-6-chloropicolinoyl chloride; 5-Chloro-6-aminonicotinic acid chloride; 6-Amino-5-chloro-3-pyridinecarboxylic acid chloride; 3-Carbamoyl-5-chloropicolinoyl chloride (related)
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarbonylchloride,6-Amino-5-Chloro-(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. Certificates of Analysis (COA) documenting all critical specifications are available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, strong oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.