Description

5-Norbornene-2-Endo-Carbonyl Chloride, 2-Chloro-Exo-3-Methyl- (6Ci) is a highly functionalized norbornene derivative, serving as a critical chiral building block and reactive intermediate in advanced organic synthesis. Its value lies in the precise stereochemistry and reactive acid chloride group, enabling the controlled construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of complex drug candidates, especially in medicinal chemistry targeting central nervous system (CNS) and anti-inflammatory applications.
• Agrochemical Synthesis: Building block for creating novel pesticides and herbicides with specific stereochemical activity.
• Polymer Science: Monomer for the production of specialty polymers with unique thermal and mechanical properties via ring-opening metathesis polymerization (ROMP).
• Material Science: Precursor for advanced materials, including liquid crystals and photoresists, where its rigid norbornene backbone is advantageous.
• Catalyst Ligand Development: Used to synthesize novel chiral ligands for asymmetric catalysis.
• Academic & R&D: Valuable reagent for methodological studies in organic synthesis and stereochemistry research.

Basic Information

Item	Detail
Product Name	5-Norbornene-2-Endo-Carbonyl Chloride, 2-Chloro-Exo-3-Methyl- (6Ci)
CAS No.	120746-19-2
Molecular Formula	C9H10Cl2O
Molecular Weight	205.08 g/mol
Synonyms	2-Chloro-exo-3-methyl-5-norbornene-2-endo-carbonyl chloride; (1S,2R,4R)-2-Chloro-1,3,3-trimethylbicyclo[2.2.1]hept-5-ene-2-carbonyl chloride; 2-Chloro-1,3,3-trimethylbicyclo[2.2.1]hept-5-ene-2-carbonyl chloride; 2-Chloro-exo-3-methyl-2-endo-norbornenecarbonyl chloride; 5-Norbornene-2-carbonyl chloride, 2-chloro-exo-3-methyl-; Bicyclo[2.2.1]hept-5-ene-2-carbonyl chloride, 2-chloro-1,3,3-trimethyl-, (1S,2R,4R)-
EINECS	Contact for details

Quality Control

Our 5-Norbornene-2-Endo-Carbonyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the exacting standards required for research and production. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.