Description

Uridine 5'-(2-Acetamido-2,6-Dideoxy-6-Fluoroglucopyranosyl)Diphosphate is a specialized nucleotide sugar derivative, a crucial activated donor substrate in enzymatic glycosylation reactions. This compound matters for its role in the biosynthesis of complex carbohydrates and glycoconjugates, enabling precise biochemical research and development. It is primarily needed by pharmaceutical researchers, biotechnology companies, and academic institutions focused on glycobiology, antiviral drug discovery, and the synthesis of novel nucleotide-based therapeutics.

Application

• Enzymatic Synthesis Substrate: Acts as a key activated sugar donor for glycosyltransferases in the synthesis of fluorinated oligosaccharides and glycopeptides.
• Glycobiology Research: Essential tool for studying enzyme kinetics, substrate specificity, and metabolic pathways involving fluorinated sugars.
• Antiviral Drug Development: Investigated as a building block or intermediate in the development of nucleoside analog prodrugs targeting viral polymerases.
• Biochemical Assay Development: Used in high-throughput screening assays to identify inhibitors or activators of specific glycosyltransferases.
• Metabolic Pathway Analysis: Employed in tracer studies to elucidate the incorporation and role of fluorinated sugars in cellular metabolism.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	Uridine 5'-(2-Acetamido-2,6-Dideoxy-6-Fluoroglucopyranosyl)Diphosphate
CAS No.	120701-60-2
Molecular Formula	C17H25FN3O16P2
Molecular Weight	608.33 g/mol
Synonyms	UDP-2-Acetamido-2,6-dideoxy-6-fluoro-α-D-glucopyranose; UDP-2-Acetamido-2,6-dideoxy-6-fluoro-D-glucose; UDP-6-Fluoro-GlcNAc; Uridine diphosphate 6-fluoro-N-acetylglucosamine; 6-Fluoro-UDP-GlcNAc; 1-[[(2R,3S,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] (2R,3S,4S,5R,6R)-5-acetamido-6-fluoro-3,4-dihydroxy-6-methyloxane-2-carboxylate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of Uridine 5'-(2-Acetamido-2,6-Dideoxy-6-Fluoroglucopyranosyl)Diphosphate is characterized and tested to meet stringent specifications for identity, purity, and potency relevant to research and development applications. Certificates of Analysis (COA) detailing purity by HPLC, NMR confirmation, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or moisture will lead to degradation. For long-term storage, consider desiccation and storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.