Description

1-Azido-2-(Chloromethyl)Benzene is a versatile bifunctional aromatic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an azido group and a chloromethyl group on the benzene ring, enables efficient participation in click chemistry reactions and nucleophilic substitutions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients, as well as for material scientists creating functional polymers and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those utilizing triazole linkages formed via copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the introduction of specific aromatic azide functionalities is required.
• Polymer & Material Science: Acts as a functional monomer or cross-linking agent for creating polymers with tailored properties, such as photo-crosslinkable resins or high-performance adhesives.
• Bioconjugation & Probe Development: Enables the labeling and modification of biomolecules (proteins, peptides, nucleic acids) for diagnostic assays and biochemical research.
• Ligand & Catalyst Preparation: Serves as a starting material for synthesizing complex ligands used in catalysis and coordination chemistry.
• Energetic Materials Research: Investigated as a component in the development of specialized energetic compounds due to the presence of the azido functional group.

Basic Information

Product Name	1-Azido-2-(Chloromethyl)Benzene
CAS No.	120692-81-1
Molecular Formula	C7H6ClN3
Molecular Weight	167.60 g/mol
Synonyms	2-(Azidomethyl)chlorobenzene; 2-Chlorobenzyl Azide; o-Chlorobenzyl Azide; (2-Chlorophenyl)methyl Azide; Azidomethyl-2-chlorobenzene; 1-Azido-2-(chloromethyl)-benzene; Benzene, 1-azido-2-(chloromethyl)-; 2-Chlorobenzylazide
EINECS	Contact for details

Quality Control

Our 1-Azido-2-(Chloromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and highly volatile; it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability and to minimize decomposition. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.