Description

Ribavirin 5'-Sulfamate CAS NO 120615-22-7 is a chemically modified nucleoside analog, specifically a sulfamate derivative of the antiviral agent ribavirin. This compound is of significant interest in pharmaceutical research and development for its potential as a prodrug or as a key intermediate in synthesizing novel antiviral therapeutics. It is primarily sought by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions engaged in antiviral drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral prodrugs and active pharmaceutical ingredients (APIs).
• Antiviral Research: Used as a reference standard or experimental compound in biochemical and virological studies to investigate mechanisms of action against RNA viruses.
• Prodrug Development: Explored for its potential to improve the pharmacokinetic profile, such as bioavailability or tissue distribution, of ribavirin-based therapies.
• Chemical Biology: Utilized in studies to understand nucleoside metabolism and the role of sulfamate modifications in biological activity.
• Process Chemistry: Acts as a key intermediate in scalable GMP (Good Manufacturing Practice) synthesis routes for advanced antiviral compounds.

Basic Information

Product Name	Ribavirin 5'-Sulfamate
CAS No.	120615-22-7
Molecular Formula	C8H12N4O8S
Molecular Weight	324.27 g/mol
Synonyms	1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(sulfamoyloxy)tetrahydrofuran-2-yl)-1H-1,2,4-triazole-3-carboxamide; Ribavirin 5'-O-Sulfamate; Ribavirin Sulfamate; 5'-O-Sulfamoylribavirin; 1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide 5'-Sulfamate
EINECS	Contact for details

Quality Control

We supply Ribavirin 5'-Sulfamate in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and impurity profiles. We can support development projects requiring material aligned with ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and protected from light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.