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Uridine 5'-(2-Acetamido-2,4-Dideoxy-4-Fluorogalactopyranosyl)Diphosphate CAS NO 120596-20-5


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CAS No.:120596-20-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Uridine 5'-(2-Acetamido-2,4-Dideoxy-4-Fluorogalactopyranosyl)Diphosphate is a specialized nucleotide sugar derivative, a key biochemical building block for the synthesis of fluorinated glycoconjugates. Its core value lies in enabling precise enzymatic glycosylation reactions, which are critical for advanced research in glycobiology and drug discovery. This high-purity intermediate is essential for pharmaceutical R&D teams, academic researchers, and biotechnology companies developing novel therapeutics, diagnostic probes, and tools for studying carbohydrate-mediated biological processes.

Application

  • Enzymatic Synthesis Substrate: Acts as a crucial donor substrate for glycosyltransferases in the enzymatic synthesis of fluorinated oligosaccharides and glycoproteins.
  • Glycobiology Research: Used as a critical reagent to study the structure, function, and biosynthesis of fluorinated carbohydrates and their role in cell signaling and recognition.
  • Pharmaceutical Development: Serves as a key intermediate in the research and development of novel fluorinated glycomimetic drugs, including potential antivirals, anti-cancer agents, and anti-inflammatory therapies.
  • Probe and Diagnostic Tool Development: Employed in the creation of metabolic labeling probes and diagnostic agents for imaging and detecting specific glycosylation patterns in cells and tissues.
  • Biocatalyst and Enzyme Mechanism Studies: Utilized to investigate the specificity and catalytic mechanisms of glycosyltransferases and other carbohydrate-processing enzymes.

Basic Information

Product Name Uridine 5'-(2-Acetamido-2,4-Dideoxy-4-Fluorogalactopyranosyl)Diphosphate
CAS No. 120596-20-5
Molecular Formula C17H25FN3O16P2
Molecular Weight 608.33 g/mol
Synonyms UDP-2-Acetamido-2,4-dideoxy-4-fluoro-α-D-galactopyranose; UDP-4-Fluoro-GalNAc; UDP-4F-GalNAc; Uridine diphosphate 4-fluoro-N-acetylgalactosamine; 4-Fluoro-UDP-GalNAc; Uridine 5'-[2-(acetylamino)-2,4-dideoxy-4-fluoro-α-D-galactopyranosyl] diphosphate
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Quality Control

Our Uridine 5'-(2-Acetamido-2,4-Dideoxy-4-Fluorogalactopyranosyl)Diphosphate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive research applications. We employ advanced analytical techniques, including HPLC, NMR, and MS, for comprehensive identity confirmation and impurity profiling. A detailed Certificate of Analysis (COA) is provided with each batch, documenting purity, assay, and critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is hygroscopic (moisture-sensitive). For long-term storage, consider storage under an inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Assay (HPLC) ≥ 90% (anhydrous basis)
Water Content (KF) ≤ 5.0%
Solubility Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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