Description

2-Amino-6-Chloro-9-(β-D-2-Deoxyribofuranosyl)Purine is a high-purity nucleoside analog building block of significant importance in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel antiviral and anticancer agents, particularly in the development of nucleoside reverse transcriptase inhibitors. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality raw materials for complex synthetic pathways. Our supply ensures consistent quality and purity to support your most demanding R&D and production processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of antiviral drugs, including nucleoside analogs targeting viral polymerases.
• Anticancer Drug Development: Used in research for creating novel chemotherapeutic agents that interfere with DNA synthesis in rapidly dividing cells.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and DNA repair mechanisms.
• Prodrug Synthesis: Serves as a core structure for developing prodrugs with improved bioavailability and targeted delivery.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Custom Synthesis Building Block: Provides a versatile starting point for medicinal chemists to create libraries of novel compounds for screening.

Basic Information

Product Name	2-Amino-6-Chloro-9-(β-D-2-Deoxyribofuranosyl)Purine
CAS No.	120595-72-4
Molecular Formula	C10H12ClN5O3
Molecular Weight	285.69 g/mol
Synonyms	2-Amino-6-chloro-9-(2-deoxy-β-D-ribofuranosyl)purine; 2-Amino-6-chloro-9-(2-deoxy-β-D-erythro-pentofuranosyl)purine; 6-Chloro-2-aminopurine-2'-deoxyriboside; 2'-Deoxy-2-amino-6-chloropurine riboside; 2-Amino-6-chloropurine deoxyriboside; Cladribine Impurity; 2-Amino-6-chloro-9H-purine-9-yl 2-deoxy-β-D-ribofuranoside
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-6-Chloro-9-(β-D-2-Deoxyribofuranosyl)Purine is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure compliance with high-purity standards suitable for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.