Description

L-Sorbose, 6-Azido-6-Deoxy- is a chemically modified derivative of L-sorbose, a key sugar intermediate, where the 6-hydroxyl group is replaced by an azido functionality. This modification creates a versatile building block, or synthon, for the synthesis of more complex molecules, particularly in pharmaceutical and fine chemical research. It is primarily utilized by research chemists and process development scientists in the life sciences sector for applications such as carbohydrate chemistry, prodrug development, and the synthesis of novel bioactive compounds. The CAS number for this specific compound is 120524-87-0.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially nucleoside analogs and other bioactive molecules.
• Carbohydrate Chemistry Research: Used as a specialized building block for constructing complex oligosaccharides, glycoconjugates, and glycomimetics.
• Click Chemistry Substrate: The azido group enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer functionalization.
• Prodrug Development: Investigated for the design of prodrugs where the azido-sorbose moiety can act as a bioreversible linker.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of chiral compounds, flavors, and fragrances requiring specific sugar-derived stereochemistry.
• Biochemical Tool Development: Useful for labeling and modifying biomolecules in research settings to study biological processes.

Basic Information

Product Name	L-Sorbose, 6-Azido-6-Deoxy-
CAS No.	120524-87-0
Molecular Formula	C6H9N3O5
Molecular Weight	203.16 g/mol
Synonyms	6-Azido-6-deoxy-L-sorbose; 6-Azido-6-deoxy-L-sorbo-hexose; 6-Azido-6-deoxy-L-sorbo-furanose; 6-Azido-6-deoxy-L-sorbofuranose; 6-Azido-L-sorbose; 6-Deoxy-6-azido-L-sorbose; L-Sorbose, 6-azido-6-deoxy-; 6-Azido-6-deoxy-L-sorbopyranose (possible tautomer)
EINECS	Contact for details

Quality Control

Our L-Sorbose, 6-Azido-6-Deoxy- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from methods such as HPLC, NMR, and IR spectroscopy. Our quality commitment ensures the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term stability, storage at 2-8°C is recommended. Keep away from heat, sparks, and open flame. Due to the presence of the azido group, standard safety precautions for azide compounds should be observed.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.