Description

2-Thiopheneethanimidoyl Chloride, n-Hydroxy-α-Oxo- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging the thiophene moiety for enhanced biological activity.
• Material Science: Acts as a building block for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene core.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes under cGMP conditions for clinical trial material production.

Basic Information

Product Name	2-Thiopheneethanimidoyl Chloride, n-Hydroxy-α-Oxo- (9Ci)
CAS No.	120450-98-8
Molecular Formula	C7H6ClNO2S
Molecular Weight	203.64 g/mol
Synonyms	2-Thiopheneglyoxylohydroximoyl Chloride; N-Hydroxy-2-thiopheneethanimidoyl Chloride; α-Oxo-2-thiopheneethanohydroximoyl Chloride; 2-Thienylglyoxal Hydroximoyl Chloride; (Hydroxyimino)(2-thienyl)acetyl Chloride; 2-Thiopheneacetohydroximoyl Chloride, α-oxo-; 120450-98-8; (Z)-N-Hydroxy-2-thiopheneacetimidoyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Thiopheneethanimidoyl Chloride, n-Hydroxy-α-Oxo- (9Ci) is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development use. Comprehensive analytical data, including HPLC purity, NMR, and MS confirmation, is generated. Certificates of Analysis (COA) are available upon request and can be tailored to meet specific project or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.