Description

Pneumocandin A(0) CAS NO 120300-08-5 is a key lipopeptide intermediate and a member of the echinocandin class of antifungal agents. This compound is of significant commercial and research interest due to its role as a precursor in the synthesis of advanced antifungal pharmaceuticals. It is primarily required by pharmaceutical R&D departments and manufacturers engaged in the development and production of novel antifungal therapies targeting invasive fungal infections.

Application

• Pharmaceutical Intermediate: Critical precursor in the semi-synthetic production of advanced echinocandin antifungal drugs, such as caspofungin.
• Antifungal Research: Serves as a reference standard and starting material in biochemical and pharmacological research focused on 1,3-β-D-glucan synthase inhibition.
• Process Development: Used in the optimization and scale-up of fermentation and purification processes within biopharmaceutical manufacturing.
• Quality Control Standard: Employed as an analytical standard in HPLC and LC-MS methods for the quality assurance of related antifungal APIs and finished drug products.

Basic Information

Item	Detail
Product Name	Pneumocandin A(0)
CAS No.	120300-08-5
Molecular Formula	C52H81N7O17
Molecular Weight	1052.2 g/mol
Synonyms	Pneumocandin A0; L-688,786; Echinocandin B; (4R,5R)-4,5-Dihydroxy-N2-((10R,12R)-10,12-dimethyl-1-oxotetradecyl)-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-(3S,4S)-3-hydroxy-4-methyl-L-prolyl-(3S,4S)-3,4-dihydroxy-L-homotyrosyl-(1S,2R)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethylamide Cyclic (6→1)-Lactone
EINECS	Contact for details

Quality Control

Our Pneumocandin A(0) is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under desiccant. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and potency. For long-term storage, consider keeping the material under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥95.0%
Related Substances (HPLC)	Total impurities ≤5.0%
Water Content (KF)	≤5.0%
Residue on Ignition	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.