Description

2',3'-o-(2,4,6-Trinitrophenyl)-8-Azidoadenosine Monophosphate is a chemically modified nucleotide analog, specifically engineered for advanced biochemical research and pharmaceutical development. This compound is valued for its unique structure, incorporating both a photoreactive azido group and a trinitrophenyl moiety, making it a critical tool for photoaffinity labeling, cross-linking studies, and enzyme inhibition assays. It is primarily sought by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on nucleotide metabolism, kinase research, and the development of novel diagnostic probes.

Application

• Photoaffinity Labeling: Acts as a crucial probe for identifying and studying nucleotide-binding sites on proteins and enzymes.
• Enzyme Inhibition Studies: Used to investigate the mechanism and kinetics of adenosine monophosphate-related enzymes, such as kinases and phosphorylases.
• Biochemical Cross-linking: Facilitates the study of protein-nucleotide interactions and complex formation under UV light.
• Nucleotide Analog Research: Serves as a key intermediate in the synthesis of novel modified nucleotides for therapeutic and diagnostic applications.
• Proteomics and Target Identification: Employed in mass spectrometry-based workflows to discover and validate drug targets.
• Antiviral and Anticancer Agent Development: Investigated as a potential precursor or active component in the design of nucleotide-based therapeutics.

Basic Information

Product Name	2',3'-o-(2,4,6-Trinitrophenyl)-8-Azidoadenosine Monophosphate
CAS No.	120229-04-1
Molecular Formula	C₁₇H₁₅N₉O₁₂P
Molecular Weight	592.28 g/mol
Synonyms	8-Azido-2',3'-O-(2,4,6-trinitrophenyl)adenosine 5'-monophosphate; 8-N₃-TNP-AMP; 8-Azido-TNP-adenosine monophosphate; 8-Azidoadenosine 2',3'-O-(2,4,6-trinitrophenyl)phosphate; TNP-8-N₃-AMP; Photoactivatable AMP analog; 8-Azido-2',3'-O-(picryl)adenosine 5'-monophosphate
EINECS	Contact for details

Quality Control

Every batch of 2',3'-o-(2,4,6-Trinitrophenyl)-8-Azidoadenosine Monophosphate is subjected to rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the exacting standards of research and development. Certificates of Analysis (COA) detailing purity, HPLC profile, and other critical parameters are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic and light-sensitive nature, the product should be handled under inert atmosphere or in a desiccator when weighing, and aliquoted to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.