Description

1,2-Di-o-Acetyl-3-Azido-3-Deoxy-5-o-Toluoyl-D-Ribofuranose is a key nucleoside derivative and a vital synthetic intermediate in advanced organic chemistry. This compound is engineered for high-precision applications where specific functional group manipulation is required. It is primarily utilized by research institutions and pharmaceutical development teams working on nucleoside analogs, antiviral agents, and complex carbohydrate chemistry.

Application

• Synthesis of Nucleoside Analogs: A crucial building block for the development of modified nucleosides with potential therapeutic activity.
• Antiviral Drug Research: Used in the research and development pipeline for novel antiviral compounds targeting specific viral enzymes.
• Carbohydrate Chemistry: Serves as a protected and activated intermediate for the stereoselective synthesis of complex sugar derivatives and oligosaccharides.
• Medicinal Chemistry & Lead Optimization: Employed to introduce the azido and ester functionalities into molecular scaffolds during structure-activity relationship (SAR) studies.
• Bioconjugation and Probe Development: The azido group allows for click chemistry applications, enabling the labeling or conjugation of biomolecules for diagnostic or research purposes.
• Process Chemistry & Scale-Up: Used in the development and optimization of synthetic routes for active pharmaceutical ingredients (APIs) at various scales.

Basic Information

Product Name	1,2-Di-o-Acetyl-3-Azido-3-Deoxy-5-o-Toluoyl-D-Ribofuranose
CAS No.	120143-22-8
Molecular Formula	C17H19N3O7
Molecular Weight	377.35 g/mol
Synonyms	1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-toluoyl-D-ribofuranose; 3-Azido-3-deoxy-1,2-di-O-acetyl-5-O-(4-methylbenzoyl)-D-ribofuranose; 5-O-p-Toluoyl-1,2-di-O-acetyl-3-azido-3-deoxy-D-ribofuranose; 3-Azido-1,2-di-O-acetyl-5-O-(p-toluoyl)-3-deoxy-D-ribofuranose; 1,2-Di-O-acetyl-3-azido-5-O-(4-methylbenzoyl)-3-deoxy-D-ribofuranose; D-Ribofuranose, 3-azido-3-deoxy-1,2-di-O-acetyl-5-O-(4-methylbenzoyl)- Azido Ribofuranose Derivative; Toluoyl Ribofuranose Intermediate
EINECS	Contact for details

Quality Control

Our 1,2-Di-o-Acetyl-3-Azido-3-Deoxy-5-o-Toluoyl-D-Ribofuranose is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.