Description

2-Amino-3-Azido-2-Methyl-Propanoic Acid is a specialized non-proteinogenic amino acid derivative featuring both amino and azido functional groups. This unique bifunctional structure makes it a valuable building block for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for applications such as peptide modification, bioconjugation, and the creation of novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Chemistry: Used for the site-specific incorporation of azide handles into peptide chains for subsequent "click chemistry" modifications.
• Bioconjugation & Probe Development: Enables the labeling of biomolecules (proteins, antibodies) with fluorescent dyes, affinity tags, or other payloads via azide-alkyne cycloaddition.
• Chemical Biology Research: Serves as a tool compound for studying biological processes and developing activity-based probes.
• Material Science: Potential monomer or cross-linker for creating functional polymers with tailored properties.
• Agrochemical Research: Intermediate in the development of new crop protection agents with novel modes of action.

Basic Information

Product Name	2-Amino-3-Azido-2-Methyl-Propanoic Acid
CAS No.	120042-13-9
Molecular Formula	C4H8N4O2
Molecular Weight	144.13 g/mol
Synonyms	2-Amino-3-azido-2-methylpropanoic acid; 2-Methyl-2-amino-3-azidopropanoic acid; 3-Azido-2-amino-2-methylpropionic acid; 2-Amino-2-methyl-3-azidopropanoic acid; Azidohomoalanine derivative; AHA derivative; Non-proteinogenic azido amino acid
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Azido-2-Methyl-Propanoic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support research and development requiring high-purity, well-characterized chemical building blocks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to minimize exposure to atmospheric humidity. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.