Description

4-(T-Butyl)-1-(4-Isothiocyanatophenyl)-2,6,7-Trioxabicyclo(2.2.2)Octane is a specialized bicyclic organic compound featuring a reactive isothiocyanate group. This chemical is valued for its role as a key synthetic intermediate and cross-linking agent in advanced material science and pharmaceutical research. It is primarily sought after by R&D chemists and process engineers in the fields of polymer chemistry, advanced coatings, and life sciences for developing novel materials with tailored properties.

Application

• Polymer Modification & Cross-linking Agent: Used to introduce reactive sites into polymer backbones for creating high-performance thermosets, adhesives, and coatings with enhanced durability and chemical resistance.
• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex drug candidates and bioactive molecules, leveraging the reactive isothiocyanate group for conjugation.
• Advanced Material Synthesis: Employed in the development of novel organic frameworks, dendrimers, and functionalized surfaces for sensors and electronic applications.
• Bioconjugation Chemistry: Acts as a linker for attaching molecules to proteins, antibodies, or other biomolecules in diagnostic assay and targeted drug delivery system development.
• Research & Development: A valuable tool for academic and industrial research in exploring new chemical reactions and material properties.

Basic Information

Product Name	4-(T-Butyl)-1-(4-Isothiocyanatophenyl)-2,6,7-Trioxabicyclo(2.2.2)Octane
CAS No.	119963-45-0
Molecular Formula	C16H19NO3S
Molecular Weight	305.39 g/mol
Synonyms	4-tert-Butyl-1-(4-isothiocyanatophenyl)-2,6,7-trioxabicyclo[2.2.2]octane; 1-(4-Isothiocyanatophenyl)-4-(tert-butyl)-2,6,7-trioxabicyclo[2.2.2]octane; tert-Butyl DBO Isothiocyanate; DBO-NCS derivative; 2,6,7-Trioxabicyclo[2.2.2]octane, 4-(1,1-dimethylethyl)-1-[4-(isothiocyanato)phenyl]-; Bicyclo[2.2.2]octane-1-isothiocyanate derivative
EINECS	Contact for details

Quality Control

Our production of 4-(T-Butyl)-1-(4-Isothiocyanatophenyl)-2,6,7-Trioxabicyclo(2.2.2)Octane adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and IR spectroscopy. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided to guarantee the material meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.