Description

Cyclopropanecarboxylic Acid, 2-(Chlorocarbonyl)-1,2-Dimethyl-, cis- (9Ci) is a high-purity, functionalized cyclopropane derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique cis-configured, multi-functional structure makes it an invaluable precursor for constructing complex molecular architectures with high stereochemical control. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to introduce the pharmacologically privileged cyclopropane ring into target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of antiviral, anticancer, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane moiety enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring high stereochemical fidelity.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-(Chlorocarbonyl)-1,2-Dimethyl-, cis- (9Ci)
CAS No.	119908-77-9
Molecular Formula	C7H9ClO3
Molecular Weight	176.60 g/mol
Synonyms	cis-2-(Chlorocarbonyl)-1,2-dimethylcyclopropanecarboxylic Acid; (1S,2S)-2-(Chlorocarbonyl)-1,2-dimethylcyclopropanecarboxylic Acid; 1,2-Dimethylcyclopropane-1,2-dicarboxylic acid chloride (cis isomer); cis-1,2-Dimethylcyclopropane-1,2-dicarboxylic acid monochloride; 119908-77-9; Cyclopropanedicarboxylic acid, 1,2-dimethyl-, 1-chloride, cis-; (1R,2R)-rel-2-(Chlorocarbonyl)-1,2-dimethylcyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of Cyclopropanecarboxylic Acid, 2-(Chlorocarbonyl)-1,2-Dimethyl-, cis- (9Ci) is manufactured and tested under a strict quality management system. We ensure compliance with high-purity research and pharmaceutical intermediate standards, with critical parameters such as chiral purity, chemical purity, and impurity profiles rigorously controlled. A comprehensive Certificate of Analysis (COA) detailing identity, assay, enantiomeric excess, and related substances is provided with each shipment to guarantee traceability and consistency for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (cis isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.