Description

2'-Methyl-2'-Deoxyidenecytidine is a modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and intermediate for the synthesis of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of nucleoside-based drugs, particularly for targeting viral polymerases and modulating cellular processes. The high-purity material is essential for ensuring the efficacy and safety of downstream pharmaceutical products.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of novel antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in the development of therapeutic agents targeting viruses such as hepatitis and herpes viruses.
• Oncology Research: Investigated as a component in prodrugs and targeted cancer therapies that interfere with DNA/RNA synthesis.
• Biochemical Tool: Employed in enzymatic studies and as a substrate analog to understand polymerase mechanisms and inhibition.
• Medicinal Chemistry: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Process Development: Used in scaling up synthetic routes for Good Manufacturing Practice (GMP) production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	2'-Methyl-2'-Deoxyidenecytidine
CAS No.	119804-96-5
Molecular Formula	C10H13N3O4
Molecular Weight	239.23 g/mol
Synonyms	2'-C-Methyl-2'-deoxycytidine; 1-(2-C-Methyl-β-D-ribofuranosyl)cytosine; 2'-Methyl-2'-deoxycytidine; 2'-C-Methylcytidine; 2'-Methylcytidine; 2'-C-Methyl-2'-deoxycytidine; NSC 760494; 2'-Methylcytidine, 2'-deoxy-
EINECS	Contact for details

Quality Control

Our 2'-Methyl-2'-Deoxyidenecytidine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development toward more stringent specifications, including those required for GMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.