Description

2,3,4-Trifluorophenyl Isothiocyanate is a versatile and highly reactive fluorinated aromatic building block. This compound is critical for introducing the trifluorophenyl isothiocyanate moiety into target molecules, enabling the synthesis of advanced materials and bioactive agents. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing novel heterocycles and functionalized intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Chelator Preparation: Serves as a precursor for creating specialized ligands used in catalysis and metal complexation studies.
• Functional Material Development: Incorporated into polymers and advanced organic materials to impart specific electronic or surface properties.
• Chemical Biology Probes: Utilized for labeling proteins or other biomolecules due to the high reactivity of the isothiocyanate group with amines.
• Custom Synthesis and Contract Research: A valuable starting material for custom synthesis houses and CROs (Contract Research Organizations) serving diverse client projects.

Basic Information

Product Name	2,3,4-Trifluorophenyl Isothiocyanate
CAS No.	119474-40-7
Molecular Formula	C7H2F3NS
Molecular Weight	197.16 g/mol
Synonyms	2,3,4-Trifluorophenyl isothiocyanate; 1-Isothiocyanato-2,3,4-trifluorobenzene; 2,3,4-Trifluorobenzene isothiocyanate; (2,3,4-Trifluorophenyl)isothiocyanate; Isothiocyanic acid, 2,3,4-trifluorophenyl ester; 2,3,4-Trifluorophenyl mustard oil
EINECS	Contact for details

Quality Control

Our 2,3,4-Trifluorophenyl Isothiocyanate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to the reactive nature of the isothiocyanate group, minimize exposure to moisture and handle under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.