Description

2-Bromo-1-(4-Fluorophenyl)-1-Butanone is a specialized organic building block featuring both bromo and fluoro substituents on a butanone scaffold. This compound matters as a versatile intermediate for synthesizing more complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides, fungicides, and pesticides where the fluorophenyl group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of monomers or functionalized molecules for advanced polymers and organic electronic materials.
• Chemical Biology Probes: Useful for the design and synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	2-Bromo-1-(4-Fluorophenyl)-1-Butanone
CAS No.	119344-67-1
Molecular Formula	C10H10BrFO
Molecular Weight	245.09 g/mol
Synonyms	2-Bromo-1-(4-fluorophenyl)butan-1-one; 4'-Fluoro-2-bromobutyrophenone; 1-(4-Fluorophenyl)-2-bromobutan-1-one; α-Bromo-4-fluorobutyrophenone; 2-Bromo-4'-fluorobutyrophenone; Butanone, 2-bromo-1-(4-fluorophenyl)-; p-Fluoro-α-bromobutyrophenone
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(4-Fluorophenyl)-1-Butanone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.