Description

1,3-Dipropyl-8-(Isothiocyanatophenyl(Aminothiocarbonyl-(2-Aminoethylaminocarbonyl-(4-Methyloxy(Phenyl)))))Xanthine CAS NO 119305-41-8 is a specialized xanthine derivative functionalized with an isothiocyanate group, making it a valuable intermediate for targeted covalent modification. This compound is engineered for high reactivity and selectivity, enabling precise conjugation in advanced research and development. It is primarily utilized by pharmaceutical and biotechnology researchers for the synthesis of novel probes, drug candidates, and diagnostic agents.

Application

• Pharmaceutical Research: Key intermediate for the synthesis of novel adenosine receptor ligands and targeted covalent inhibitors.
• Bioconjugation: Used to covalently label proteins, antibodies, or peptides via its reactive isothiocyanate group for probe development.
• Chemical Biology: Serves as a building block for creating activity-based probes (ABPs) to study enzyme function and target engagement.
• Diagnostic Agent Development: Employed in the design and synthesis of contrast agents or molecular imaging probes.
• High-Throughput Screening: Utilized as a scaffold or reference compound in drug discovery libraries.
• Academic Research: Fundamental tool for investigating purinergic signaling pathways and receptor biology.

Basic Information

Product Name	1,3-Dipropyl-8-(Isothiocyanatophenyl(Aminothiocarbonyl-(2-Aminoethylaminocarbonyl-(4-Methyloxy(Phenyl)))))Xanthine
CAS No.	119305-41-8
Molecular Formula	C27H31N7O4S2
Molecular Weight	581.71 g/mol
Synonyms	8-(4-Isothiocyanatophenyl)-1,3-dipropylxanthine; Xanthine amine congener isothiocyanate; XAC isothiocyanate; 1,3-Dipropyl-8-[4-[[[(2-aminoethyl)amino]carbonyl]amino]phenyl]xanthine isothiocyanate; DPCPX isothiocyanate derivative; Adenosine receptor antagonist derivative; A1 adenosine receptor antagonist probe
EINECS	Contact for details

Quality Control

Our production of 1,3-Dipropyl-8-(Isothiocyanatophenyl(Aminothiocarbonyl-(2-Aminoethylaminocarbonyl-(4-Methyloxy(Phenyl)))))Xanthine adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC purity analysis, NMR structural confirmation, and mass spectrometry verification. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and key physicochemical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccated conditions. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store under an inert atmosphere. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in alcohols

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.