Description

Spiro[Cyclopropane-1,3-[3H]Indole]-1(2H)-Carbonyl Chloride (9Ci) is a specialized spirocyclic indole derivative featuring a highly reactive carbonyl chloride functional group. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block for constructing complex molecular architectures. It is primarily utilized by research organizations and fine chemical manufacturers engaged in the development of novel bioactive molecules, particularly in medicinal chemistry and agrochemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of spirocyclic drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Agrochemical Synthesis: Intermediate in the production of novel pesticides and herbicides with spirocyclic frameworks.
• Organic Synthesis Reagent: Acts as an acylating agent for introducing the spiro[cyclopropane-1,3'-indole] moiety into more complex molecules.
• Material Science Precursor: Potential starting material for creating specialized polymers or organic electronic materials with unique indole-based structures.

Basic Information

Product Name	Spiro[Cyclopropane-1,3-[3H]Indole]-1(2H)-Carbonyl Chloride (9Ci)
CAS No.	119199-52-9
Molecular Formula	C11H8ClNO
Molecular Weight	205.64 g/mol
Synonyms	1H-Spiro[cyclopropane-1,3'-indole]-1'-carbonyl chloride; 1'H-Spiro[cyclopropane-1,3'-indole]-1'-carbonyl chloride; Spiro[cyclopropane-1,3'-[3H]indole]-1'(2'H)-carbonyl chloride; 1-Azaspiroundecane-1-carbonyl chloride derivative; 1H-Spiro[cyclopropane-1,3'-indol]-1'-carbonyl chloride; Spiro(cyclopropane-1,3'-(3'H)-indole)-1'-carbonyl chloride
EINECS	Contact for details

Quality Control

Our Spiro[Cyclopropane-1,3-[3H]Indole]-1(2H)-Carbonyl Chloride (9Ci) is manufactured under strict quality control protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and moisture-sensitive nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.