Description

1-Azabicyclo[2.2.1]Heptane-4-Carbonyl Chloride (9Ci) is a specialized bicyclic organic compound that serves as a high-value building block in advanced chemical synthesis. Its unique bridged-ring structure and reactive carbonyl chloride group make it a critical intermediate for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its rigid bicyclic framework can contribute to biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemical control.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and for exploring new reaction pathways.
• Peptidomimetic Scaffolds: Its structure is useful for designing and synthesizing peptidomimetics and conformationally restricted peptide analogs.

Basic Information

Product Name	1-Azabicyclo[2.2.1]Heptane-4-Carbonyl Chloride (9Ci)
CAS No.	119103-16-1
Molecular Formula	C7H10ClNO
Molecular Weight	159.61 g/mol
Synonyms	4-(Chlorocarbonyl)-1-azabicyclo[2.2.1]heptane; 1-Azabicyclo[2.2.1]heptane-4-carboxylic acid chloride; endo-3-Aminonorbornane-2-carboxylic acid chloride derivative; Bicyclo[2.2.1]heptane-2-carboxylic acid, 3-amino-, chloride (1:1); 1-Azanorbornane-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[2.2.1]Heptane-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Solubility	Soluble in common organic solvents (DCM, THF, Acetone)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.