Description

1-Azabicyclo[3.3.1]Nonane-5-Carbonyl Chloride (9Ci) is a specialized bicyclic organic compound featuring a reactive carbonyl chloride functional group, making it a valuable building block in advanced organic synthesis. Its unique bridged nitrogen-containing structure is critical for constructing complex molecular architectures with specific three-dimensional properties. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those requiring rigid, bridged amine scaffolds for enhanced biological activity and selectivity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where its bicyclic structure contributes to stability and efficacy.
• Chemical Research & Development: Serves as a versatile building block in academic and industrial R&D for exploring new chemical spaces and reaction methodologies.
• Peptidomimetics & Bioactive Molecule Design: Employed to create conformationally restricted peptide analogs and other bioactive compounds that mimic natural substrates.
• Ligand & Catalyst Development: Useful for synthesizing novel chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.

Basic Information

Product Name	1-Azabicyclo[3.3.1]Nonane-5-Carbonyl Chloride (9Ci)
CAS No.	119103-13-8
Molecular Formula	C9H12ClNO
Molecular Weight	185.65 g/mol
Synonyms	1-Azabicyclo[3.3.1]nonane-5-carbonyl chloride; 1-Azabicyclo[3.3.1]nonane-5-carboxylic acid chloride; 5-Carboxy-1-azabicyclo[3.3.1]nonane chloride; 9CI-119103-13-8; Bicyclo[3.3.1]azanonane-5-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[3.3.1]Nonane-5-Carbonyl Chloride (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. We provide Certificates of Analysis (COA) with detailed specifications for traceability and quality assurance, supporting cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.