Description

Abanoquil CAS NO 118931-00-3 is a selective and potent α-2 adrenergic receptor antagonist used in advanced pharmacological research. This compound is valued for its high specificity, making it a critical tool for studying autonomic nervous system regulation and cardiovascular function. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and contract research organizations (CROs) focused on neuropharmacology and cardiovascular drug discovery.

Application

• Pharmacological Research: As a reference standard in studies investigating α-2 adrenoceptor mechanisms and signal transduction pathways.
• Cardiovascular Studies: Used in preclinical models to explore the role of α-2 receptors in blood pressure regulation and vascular tone.
• Neuropharmacology: A key compound for researching central and peripheral nervous system interactions, including studies on sedation, analgesia, and sympathetic outflow.
• Drug Discovery & Development: Serves as a lead compound or biochemical tool for screening and developing new therapeutic agents targeting adrenergic receptors.
• Academic & Institutional Research: Employed in university and government labs for fundamental scientific research and educational purposes.
• Biochemical Assay Development: Used to validate and calibrate assays for receptor binding and functional activity.

Basic Information

Product Name	Abanoquil
CAS No.	118931-00-3
Molecular Formula	C19H21N3O2
Molecular Weight	323.39 g/mol
Synonyms	Abanoquil; Abanoquil hydrochloride; (R)-Abanoquil; (R)-2-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-2,3-dihydro-1-methyl-1H-isoindole; 2-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-1-methylisoindoline; BRL-44048; BRL 44048; UK-52046
EINECS	Contact for details

Quality Control

Our Abanoquil is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR). A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and strength.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. Keep the container sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.