Description

1H-1,2,4-Triazole-1-Carbonyl Chloride, 3-(Dimethylamino)-4,5-Dihydro-4-Methyl-5-Oxo- (9Ci) is a highly reactive and versatile chemical intermediate, specifically a functionalized triazole carbonyl chloride derivative. Its value lies in its ability to act as a key building block for the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working on novel active ingredients, heterocyclic compounds, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Serves as a key building block for developing new generations of herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Heterocyclic Chemistry Research: Used extensively in academic and industrial laboratories for constructing complex triazole-based heterocyclic scaffolds for material science and medicinal chemistry.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals, including dyes, pigments, and performance materials requiring specific triazole functionalities.
• Ligand and Catalyst Development: Useful for creating novel ligands for metal catalysis or as a component in organocatalysts due to its reactive carbonyl chloride and dimethylamino groups.

Basic Information

Product Name	1H-1,2,4-Triazole-1-Carbonyl Chloride, 3-(Dimethylamino)-4,5-Dihydro-4-Methyl-5-Oxo- (9Ci)
CAS No.	118846-72-3
Molecular Formula	C7H9ClN4O2
Molecular Weight	216.63 g/mol
Synonyms	3-(Dimethylamino)-4,5-dihydro-4-methyl-5-oxo-1H-1,2,4-triazole-1-carbonyl chloride; 1H-1,2,4-Triazole-1-carbonyl chloride, 3-(dimethylamino)-4,5-dihydro-4-methyl-5-oxo-; 3-(Dimethylamino)-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazole-1-carbonyl chloride; 118846-72-3; AKOS BBS-00007719; 1-Carboxy-3-dimethylamino-4-methyl-δ²-1,2,4-triazolin-5-one chloride; AS-80533; ZINC000103014509
EINECS	Contact for details

Quality Control

Our 1H-1,2,4-Triazole-1-Carbonyl Chloride, 3-(Dimethylamino)-4,5-Dihydro-4-Methyl-5-Oxo- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO guidelines ensures the material meets the high standards required for pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.