Description

4-Isothiocyanato-1-Methylpiperidine is a specialized organic building block featuring a reactive isothiocyanate group attached to a methylpiperidine scaffold. This compound is valued for its role as a versatile intermediate in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by research chemists and process development scientists in the life sciences sector for constructing novel chemical entities and potential active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting neurological and metabolic disorders.
• Chemical Biology Probe Synthesis: Used to create isothiocyanate-functionalized probes for labeling and studying biological targets, such as proteins and enzymes.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides, leveraging the reactivity of the isothiocyanate group.
• Material Science: Can be utilized in the surface modification of polymers or nanoparticles to introduce specific functional groups.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized ligands for metal-catalyzed reactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	4-Isothiocyanato-1-Methylpiperidine
CAS No.	118705-17-2
Molecular Formula	C7H12N2S
Molecular Weight	156.25 g/mol
Synonyms	1-Methyl-4-isothiocyanatopiperidine; 4-Isothiocyanato-1-methylpiperidine; 1-Methylpiperidine-4-isothiocyanate; N-Methyl-4-piperidyl isothiocyanate; 4-Isothiocyanato-N-methylpiperidine; 1-Methyl-4-piperidyl isothiocyanate; 4-(Isothiocyanato)-1-methylpiperidine
EINECS	Contact for details

Quality Control

Our 4-Isothiocyanato-1-Methylpiperidine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.