Description

Cyclopentanecarboxylic Acid, 2-(Chlorocarbonyl)-, cis- (9Ci) is a high-purity, cis-configured carboxylic acid derivative featuring a reactive acid chloride functional group. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate, enabling the synthesis of complex, stereochemically defined molecules. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemistry and high functional group reactivity for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the cis-cyclopentane scaffold imparts specific biological activity.
• Fine Chemical Manufacturing: Serves as a versatile building block for synthesizing complex fragrance compounds, specialty polymers, and liquid crystals.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, asymmetric catalysis, and medicinal chemistry programs.
• Peptidomimetic & Prodrug Development: The reactive carbonyl chloride group facilitates coupling reactions to create peptide analogs and prodrug linkers.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-(Chlorocarbonyl)-, cis- (9Ci)
CAS No.	118577-38-1
Molecular Formula	C7H9ClO3
Molecular Weight	176.60 g/mol
Synonyms	cis-2-(Chlorocarbonyl)cyclopentanecarboxylic Acid; (1R,2S)-2-(Chlorocarbonyl)cyclopentanecarboxylic Acid (for one enantiomer); 2-Carboxycyclopentane-1-carbonyl Chloride, cis-; Cyclopentane-1,2-dicarboxylic Acid 1-Chloride, cis-; 1,2-Cyclopentanedicarboxylic Acid, 1-Chloride, cis-; cis-1,2-Cyclopentanedicarboxylic Acid Monoacid Chloride; 118577-38-1; cis-Cyclopentane-1,2-dicarboxylic acid 1-chloride
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxylic Acid, 2-(Chlorocarbonyl)-, cis- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and assay determination, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with strong bases and nucleophiles; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain purity and reactivity. Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% cis-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.