Description

1,3-Benzodioxole-2-Carbonyl Chloride (9Ci) is a versatile and highly reactive acyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce the 1,3-benzodioxole moiety, a privileged structural motif, into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the benzodioxole group can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer and Material Science: Employed to functionalize polymers or surfaces, imparting specific chemical properties for advanced material applications.
• Organic Synthesis Building Block: A fundamental reagent for constructing heterocyclic compounds, amides, and esters in research and development laboratories.
• Flavor and Fragrance Chemistry: Potential intermediate in the synthesis of complex aroma chemicals and flavoring agents.

Basic Information

Product Name	1,3-Benzodioxole-2-Carbonyl Chloride (9Ci)
CAS No.	118507-58-7
Molecular Formula	C8H5ClO3
Molecular Weight	184.58 g/mol
Synonyms	1,3-Benzodioxole-2-carbonyl chloride; 2-Piperonyloyl chloride; Piperonyloyl chloride; 1,3-Benzodioxol-2-carbonyl chloride; 2-Carboxy-1,3-benzodioxole chloride; 3,4-Methylenedioxybenzoyl chloride; (1,3-Benzodioxol-2-yl)carbonyl chloride; Piperonyl chloride
EINECS	Contact for details

Quality Control

Our 1,3-Benzodioxole-2-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.